The Fingert lab led a study of pigmentary glaucoma that scanned through every gene in the genomes of hundreds of patients with pigmentary glaucoma in search of disease-causing defects. The results of the study have been published in BMC genomics this month. This study identified MRAP (melanocortin 2 receptor accessory protein) as a new potential contributor to pigmentary glaucoma. It is highly produced in the iris - the source of the pigment released in the eye in pigmentary glaucoma (see photo above). Read more about this discovery here.
Thu, 07/15/2021 - 14:15
Thu, 03/12/2020 - 15:30
Wed, 11/06/2019 - 10:45Lab discovers first genetic risk factor for glaucoma that is unique to patients with African Ancestry
The Fingert and Mullins Labs collaborated with investigators from Duke University, Singapore, and from around the world to identify the first genetic risk factor for glaucoma that is unique to people with African ancestry - a population group with highest prevalence of glaucoma and most severe disease. Notably, the newly identified glaucoma risk factor, APBB2, has important links with the biology of another degenerative condition, Alzheimer’s disease. This major advance in glaucoma research was published in the Journal of the American Medical Association. Read more about it here.