Recent News

  • Fingert Lab News
    Thursday, January 30, 2014 - 15:00

    We recently published a report of our stem-cell based studies of glaucoma in the prestigious JOURNAL OF STEM CELL RESEARCH & THERAPY.

    Normal tension glaucoma is a disease of the optic nerve that occurs without high pressure in the eye. We previously discovered that a duplication of the TBK1 gene is responsible for some cases of normal tension glaucoma. We believe that the TBK1 gene duplication alters the metabolism of the optic nerve and causes glaucoma.

    In this new publication we report the first example of using adult stem-cell technology to grow optic nerve cells (retinal ganglion cells) from a glaucoma patient’s skin in a culture dish. We have grown optic nerve cells from a skin biopsy taken from one of our patient’s that has normal tension glaucoma caused by a TBK1 gene duplication. This major development has provided us with the means to use laboratory methods to study what goes wrong in the optic nerve cells of patients with TBK1 gene duplications.

    A copy of our article describing this work is available here.

  • Fingert Lab News
    Friday, December 6, 2013 - 14:30
  • Fingert Lab News
    Thursday, October 24, 2013 - 08:45

    Dr. Fingert presented stem cell research of glaucoma disease mechanisms at the 2013 meeting of the American Society for Human Genetics in Boston. The Glaucoma Genetics Laboratory is collaborating with Budd Tucker and his ophthalmic stem cell lab to study glaucoma. Three major advances in the team's stem cell research of glaucoma were presented.

  • Fingert Lab News
    Wednesday, October 9, 2013 - 15:15

    Dr. Fingert was among the clinical researchers to be elected to the American Society for Clinical Investigation.

    The American Society for Clinical Investigation (ASCI), established in 1908, is one of the nation's oldest and most respected medical honor societies.

  • General News
    Wednesday, October 9, 2013 - 15:15

    A research group led by investigator Takeshi Iwata recently reported studies of the role of the optineurin gene in normal tension glaucoma using stem cell and transgenic mouse approaches. Their study advanced and confirmed that optineurin and TBK1 genes are glaucoma genes and that their interaction is important in the development of normal tension glaucoma. Read more about the report here.